Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of DRD2 in mouse tissue homogenates, cell lysates.
Target Information: This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia\, other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]